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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1992-5-5
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pubmed:abstractText |
The efficacy and safety of fluconazole, a new triazole antifungal agent, was evaluated in 24 patients with neutropenia due to cytotoxic anticancer chemotherapy with polyfactorial immunodepression. Twenty of 23 patients benefited from treatment, and except for 1 patient with mild abdominal discomfort the drug was well tolerated. Mycological eradication appeared in 17 from 23 evaluable patients, superinfection in 1 case and persistence could be evaluated in 5 cases. Candida albicans, C. crusei and C. pseudotropicalis together with Torulopsis sp. were the most frequently isolated organisms from pharyngeal and esophageal mucosa in treated patients with oropharyngeal and esophageal mycosis.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0009-3157
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-5
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:1804594-Administration, Oral,
pubmed-meshheading:1804594-Adult,
pubmed-meshheading:1804594-Antineoplastic Agents,
pubmed-meshheading:1804594-Candidiasis, Oral,
pubmed-meshheading:1804594-Drug Evaluation,
pubmed-meshheading:1804594-Esophagitis,
pubmed-meshheading:1804594-Female,
pubmed-meshheading:1804594-Fluconazole,
pubmed-meshheading:1804594-Humans,
pubmed-meshheading:1804594-Injections, Intravenous,
pubmed-meshheading:1804594-Male,
pubmed-meshheading:1804594-Mycoses,
pubmed-meshheading:1804594-Neoplasms,
pubmed-meshheading:1804594-Neutropenia,
pubmed-meshheading:1804594-Pharyngitis
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pubmed:year |
1991
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pubmed:articleTitle |
Fluconazole in the treatment of mycotic oropharyngeal stomatitis and esophagitis in neutropenic cancer patients.
|
pubmed:affiliation |
Department of Clinical Oncology, Postgraduate Medical Institute, Bratislava, CSFR.
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pubmed:publicationType |
Journal Article
|