Source:http://linkedlifedata.com/resource/pubmed/id/18039607
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2007-11-27
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pubmed:abstractText |
We have determined the concentration of Lp(a) in an Ivory Coast population (n=102) using two immunochemical methods: Laurell's monodimensional electro-immunodiffusion (EID) and immunonephelometry (IN). Within-run and between-run precision was respectively 3.07% and 3.97% by IN and 1.52% and 4.48% by EID method. As regard the exactitude, the bias goals in two methods were 3.5% and 3.0% respectively with IN and EID. The two methods were correlated (r=0.84; p=0.006). Mean values of Lp(a) were significantly (p=0.0007) higher by IN than EID: 0.48+/-0.34 g/L versus 0.32+/-0.19 g/L. The Lp(a) distributions were non-Gaussian, skewed towards high values, with median value of 0.47 g/L and 0.32 g/L respectively for IN and EID methods. Therefore, we conclude that although both methods showed a satisfactory precision, and results were correlated, Lp(a) values were higher by INP. Furthermore, mean values of Lp(a) in presumed healthy Ivorian is higher than in Caucasians.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0003-3898
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
629-35
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pubmed:meshHeading |
pubmed-meshheading:18039607-Adolescent,
pubmed-meshheading:18039607-Adult,
pubmed-meshheading:18039607-Cote d'Ivoire,
pubmed-meshheading:18039607-Humans,
pubmed-meshheading:18039607-Immunoassay,
pubmed-meshheading:18039607-Immunodiffusion,
pubmed-meshheading:18039607-Lipoprotein(a),
pubmed-meshheading:18039607-Middle Aged,
pubmed-meshheading:18039607-Nephelometry and Turbidimetry,
pubmed-meshheading:18039607-Reference Values,
pubmed-meshheading:18039607-Reproducibility of Results,
pubmed-meshheading:18039607-Sensitivity and Specificity
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pubmed:articleTitle |
[Immunoquantification of serum lipoprotein(a) in healthy Ivorian subject: a comparative evaluation of two methods].
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pubmed:affiliation |
Laboratoire de biochimie, UFR de sciences pharmaceutiques et biologiques, Abidjan, Ivory Coast.
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pubmed:publicationType |
Journal Article,
English Abstract
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