pubmed-article:18035413 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0033325 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0152035 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0023467 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0919534 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C1333715 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C2825097 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C0678951 | lld:lifeskim |
pubmed-article:18035413 | lifeskim:mentions | umls-concept:C1515568 | lld:lifeskim |
pubmed-article:18035413 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:18035413 | pubmed:dateCreated | 2008-5-7 | lld:pubmed |
pubmed-article:18035413 | pubmed:abstractText | We investigated the prognostic significance of genetic polymorphism for glutathione S-transferase theta 1 (GSTT1) and glutathione S-transferase mu 1 (GSTM1) in 254 Chinese patients with de novo acute myeloid leukemia (AML) other than AML-M3. The early death rate after the initiation of chemotherapy was similar between the GSTT1+/GSTM1+ group and GSTT1-/GSTM1- group. The complete remission (CR) rate was higher in GSTM1+ group than in GSTM1- group (OR=1.88; P=0.03) after the first course of chemotherapy, and was higher in GSTT1+ group than in GSTT1- group (OR=2.20; P=0.02) after the second course of chemotherapy. Overall survival and disease-free survival of CR patients in GSTT1 and GSTM1 double present group was better than in GSTT1- and/or GSTM1-group (P=0.03 and 0.02, respectively). Our preliminary results warrant testing of a larger number of patients. | lld:pubmed |
pubmed-article:18035413 | pubmed:language | eng | lld:pubmed |
pubmed-article:18035413 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18035413 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:18035413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18035413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18035413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18035413 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:18035413 | pubmed:month | Aug | lld:pubmed |
pubmed-article:18035413 | pubmed:issn | 0145-2126 | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:JooFF | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:WangJianxiang... | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:YangLinL | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:HaoYushuY | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:XiaoZhijianZ | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:ZhangYueY | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:LiuLiangL | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:XuZefengZ | lld:pubmed |
pubmed-article:18035413 | pubmed:author | pubmed-author:NieLingL | lld:pubmed |
pubmed-article:18035413 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:18035413 | pubmed:volume | 32 | lld:pubmed |
pubmed-article:18035413 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:18035413 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:18035413 | pubmed:pagination | 1288-91 | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
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pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:meshHeading | pubmed-meshheading:18035413... | lld:pubmed |
pubmed-article:18035413 | pubmed:year | 2008 | lld:pubmed |
pubmed-article:18035413 | pubmed:articleTitle | Glutathione S-transferases (GSTT1 and GSTM1) genes polymorphisms and the treatment response and prognosis in Chinese patients with de novo acute myeloid leukemia. | lld:pubmed |
pubmed-article:18035413 | pubmed:affiliation | State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. zjxiao@hotmail.com | lld:pubmed |
pubmed-article:18035413 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:18035413 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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