Linked Life Data

18035385

Source:http://linkedlifedata.com/resource/pubmed/id/18035385

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-12-6
pubmed:abstractText
New antimalarial treatments are now urgently required, following the emergence of resistance to the most used drugs. Natural products contribute greatly to the therapeutic arsenal in this area, including artemisinin and quinine (and atovaquone, semi-synthetic). Among the natural products, indole alkaloids represent an interesting class of compounds. Screening carried out to date has revealed several substances active in vitro under the micromolar range and with a good selectivity index. This review covers the indole alkaloids with high antiplasmodial activity (in vitro and in vivo) isolated from natural sources, and is organized according to the different chemical structures of the alkaloids.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Potential antimalarial activity of indole alkaloids.
pubmed:affiliation
Université de Liège, Centre Interfacultaire de Recherche du Médicament (CIRM), Département de Pharmacie, CHU - Tour 4 - Bâtiment B36, Avenue de l'Hôpital, 1 - B4000 Liège, Belgium. m.frederich@ulg.ac.be
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't