rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
2007-11-21
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pubmed:abstractText |
Insulin stimulates cerebrocortical beta and theta activity in lean humans. This effect is reduced in obese individuals indicating cerebrocortical insulin resistance. In the present study we tested whether insulin detemir is a suitable tool to restore the cerebral insulin response in overweight humans. This approach is based on studies in mice where we could recently demonstrate increased brain tissue concentrations of insulin and increased insulin signaling in the hypothalamus and cerebral cortex following peripheral injection of insulin detemir.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18030331-10662720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18030331-10766253,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18030331-9726588
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1932-6203
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e1196
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
|
pubmed:year |
2007
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pubmed:articleTitle |
Cerebrocortical beta activity in overweight humans responds to insulin detemir.
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pubmed:affiliation |
Department of Internal Medicine IV, University of Tübingen, Tübingen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|