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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-11-21
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pubmed:abstractText |
The variation of venom composition with geography is an important aspect of intraspecific variability in the Vipera genus, although causes of this variability remain unclear. The diversity of snake venom is important both for our understanding of venomous snake evolution and for the preparation of relevant antivenoms to treat envenomations. A geographic intraspecific variation in snake venom composition was recently reported for Vipera aspis aspis venom in France. Since 1992, cases of human envenomation after Vipera aspis aspis bites in south-east France involving unexpected neurological signs were regularly reported. The presence of genes encoding PLA(2) neurotoxins in the Vaa snake genome led us to investigate any neurological symptom associated with snake bites in other regions of France and in neighboring countries. In parallel, we used several approaches to characterize the venom PLA(2) composition of the snakes captured in the same areas.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18030329-10078860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18030329-11249011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18030329-11679719,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18030329-11883370,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18030329-9765647
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e1194
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18030329-Animals,
pubmed-meshheading:18030329-Base Sequence,
pubmed-meshheading:18030329-DNA Primers,
pubmed-meshheading:18030329-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:18030329-Mass Spectrometry,
pubmed-meshheading:18030329-Neurotoxins,
pubmed-meshheading:18030329-Phospholipases A2,
pubmed-meshheading:18030329-RNA, Messenger,
pubmed-meshheading:18030329-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18030329-Viper Venoms
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pubmed:year |
2007
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pubmed:articleTitle |
Reappraisal of Vipera aspis venom neurotoxicity.
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pubmed:affiliation |
Unité des Venins, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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