Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-12-6
pubmed:abstractText
This paper develops a simple mathematical model of the sitting of capillary sprouts on an existing blood vessel during the initiation of tumour-induced angiogenesis. The model represents an inceptive attempt to address the question of how unchecked sprouting of the parent vessel is avoided at the initiation of angiogenesis, based on the idea that feedback regulation processes play the dominant role. No chemical interaction between the proangiogenic and antiangiogenic factors is assumed. The model is based on corneal pocket experiments, and provides a mathematical analysis of the initial spacing of angiogenic sprouts.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-5193
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
250
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-15
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
A simple mechanistic model of sprout spacing in tumour-associated angiogenesis.
pubmed:affiliation
School of Mathematical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane 4001, Australia. b.addison-smith@qut.edu.au <b.addison-smith@qut.edu.au>
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't