Linked Life Data

18023348

Source:http://linkedlifedata.com/resource/pubmed/id/18023348

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-1-9
pubmed:abstractText
Several carbamate derivatives of 4-aminopyridine were synthesized and their anticholinesterase activity was evaluated. Compound 4d showed the highest inhibitory effect blocking non-competitively acetylcholinesterase and competitively butyrylcholinesterase. Furthermore, carbamate 4d was able to revert the amnesic effects of scopolamine in the passive avoidance test in rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1464-3405
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-12
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity.
pubmed:affiliation
Dipartimento di Studi di chimica e tecnologia delle sostanze biologicamente attive, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italia. luigi.scipione@uniroma1.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't