Linked Life Data

17989919

Source:http://linkedlifedata.com/resource/pubmed/id/17989919

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-1-25
pubmed:abstractText
Menkes disease is caused by mutations in the copper-transporting P(1B)-type ATPase ATP7A. ATP7A has a dual function: it serves to incorporate copper into copper-dependent enzymes, and it maintains intracellular copper levels by removing excess copper from the cytosol. To accomplish both functions, the protein traffics between different cellular locations depending on copper levels. The mechanism for sensing the concentration of copper, for trafficking, as well as the details of the mechanism of copper translocation across the membrane are unknown.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1420-682X
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-91
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Menkes disease.
pubmed:affiliation
Magnetic Resonance Center (CERM), University of Florence, Via L.Sacconi 6, 50019, Sesto Fiorentino, Italy. ivanobertini@cerm.unifi.it
pubmed:publicationType
Journal Article, Review