Linked Life Data

17989037

Source:http://linkedlifedata.com/resource/pubmed/id/17989037

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-11-8
pubmed:abstractText
Gene targeting, which allows the efficient modification of specific murine genes, plays important roles in elucidating physiological function of genes in vivo, dissecting the genetic mechanisms of human disease and identifying potential targets for drug development. In recent years, the development of conditional gene targeting has provided novel opportunities for gene inactivation in specific cells or organs, and at specific time points, both during development and in the adult animals. In this review, we introduce the history of gene targeting and recent progress of gene targeting technology and its applications in other model organisms.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1291-8
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[Gene targeting: the beginning of a new era in genetics].
pubmed:affiliation
Genetic Laboratory of Development and Diseases, Beijing Institute of Biotechnology, Beijing 100071, China. tengyan0919@tom.com
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't