rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-1-21
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pubmed:abstractText |
The comparison of complete genomes has revealed surprisingly large numbers of conserved non-protein-coding (CNC) DNA regions. However, the biological function of CNC remains elusive. CNC differ in two aspects from conserved protein-coding regions. They are not conserved across phylum boundaries, and they do not contain readily detectable sub-domains. Here we characterize the persistence length and time of CNC and conserved protein-coding regions in the vertebrate and insect lineages.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17973996-11928468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17973996-12466853,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17973996-12529312,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17973996-9482889
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
398
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17973996-Animals,
pubmed-meshheading:17973996-Conserved Sequence,
pubmed-meshheading:17973996-DNA, Intergenic,
pubmed-meshheading:17973996-Drosophila,
pubmed-meshheading:17973996-Evolution, Molecular,
pubmed-meshheading:17973996-Genome,
pubmed-meshheading:17973996-Genome, Insect,
pubmed-meshheading:17973996-Humans,
pubmed-meshheading:17973996-Time Factors,
pubmed-meshheading:17973996-Vertebrates
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pubmed:year |
2007
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pubmed:articleTitle |
Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time.
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pubmed:affiliation |
Computational Cancer Genomics Group, Swiss Institute of Bioinformatics, Lausanne, Switzerland. Dorota.Retelska@isrec.ch
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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