|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0025598,
umls-concept:C0032173,
umls-concept:C0087111,
umls-concept:C0205216,
umls-concept:C0242606,
umls-concept:C0332307,
umls-concept:C0392386,
umls-concept:C0681850,
umls-concept:C1515655,
umls-concept:C1518321,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2008-3-3
|
|
pubmed:abstractText |
In type 2 diabetes, metformin reduces cardiovascular risk beyond the effect of glycaemic control. Since oxidative stress and the consequent enhanced platelet activation contribute to accelerated atherosclerosis in diabetes, we hypothesized that metformin could reduce oxidative stress in this condition.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1520-7552
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright (c) 2008 John Wiley & Sons, Ltd.
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
231-7
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:17966969-Aged,
pubmed-meshheading:17966969-Blood Glucose,
pubmed-meshheading:17966969-C-Peptide,
pubmed-meshheading:17966969-Diabetes Mellitus, Type 2,
pubmed-meshheading:17966969-Female,
pubmed-meshheading:17966969-Gliclazide,
pubmed-meshheading:17966969-Glucose Tolerance Test,
pubmed-meshheading:17966969-Humans,
pubmed-meshheading:17966969-Hypoglycemic Agents,
pubmed-meshheading:17966969-Insulin,
pubmed-meshheading:17966969-Male,
pubmed-meshheading:17966969-Metformin,
pubmed-meshheading:17966969-Middle Aged,
pubmed-meshheading:17966969-Oxidative Stress,
pubmed-meshheading:17966969-Platelet Activation
|
|
pubmed:articleTitle |
Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects.
|
|
pubmed:affiliation |
Department of Medicine and Aging Sciences, University -G. d'Annunzio, Chieti, Italy.
|
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
