Linked Life Data

17958642

Source:http://linkedlifedata.com/resource/pubmed/id/17958642

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-10-25
pubmed:abstractText
The human hepatitis B virus is a small, enveloped and non-cytopathic virus, with a very narrow host range and a strong liver tropism causing acute and chronic liver disease. Although a well-tolerated vaccine is available, more than 350 million people are chronically infected worldwide. Available therapies for chronic hepatitis B only rarely eliminate the virus. Although new antivirals are being developed, long-term treatment is required, which may be limited by the selection of resistant viruses. Therefore, immunotherapies are investigated as an approach to eliminate persistently infected cells. Besides therapeutic vaccination, adoptive T-cell therapy is an interesting option, which is discussed in this review.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1352-0504
pubmed:author
pubmed:issnType
Print
pubmed:volume
14 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-50
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Adoptive T-cell therapy as a therapeutic option for chronic hepatitis B.
pubmed:affiliation
Centre for Molecular Medicine, Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't