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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-10-24
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pubmed:abstractText |
The diagnosis of acute osteomyelitis and septic arthritis is a clinical one. Acute-phase reactants, such as white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) are useful to help the clinicians at the time of initial diagnosis. The WBC count may be normal in up to 80 % of cases and it is not a reliable indicator. The ESR is elevated in 80 % of cases. CRP is elevated more than 80 % of cases. CRP rises rapidly within 48 hours of admission and returns to normal within a week after appropriate therapy. Its rapid kinetics is useful for follow-up of the response treatment. Patients who require surgical drainage procedures have prolonged time to normalization of CRP. PCT is a useful specific marker for predicting severe infection but its sensibility to detect bone and joint infections seems to be low.
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pubmed:language |
fre
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0929-693X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S86-90
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pubmed:meshHeading |
pubmed-meshheading:17956824-Acute Disease,
pubmed-meshheading:17956824-Administration, Oral,
pubmed-meshheading:17956824-Age Factors,
pubmed-meshheading:17956824-Anti-Bacterial Agents,
pubmed-meshheading:17956824-Arthritis, Infectious,
pubmed-meshheading:17956824-Biological Markers,
pubmed-meshheading:17956824-Blood Sedimentation,
pubmed-meshheading:17956824-C-Reactive Protein,
pubmed-meshheading:17956824-Calcitonin,
pubmed-meshheading:17956824-Child,
pubmed-meshheading:17956824-Child, Preschool,
pubmed-meshheading:17956824-Diagnosis, Differential,
pubmed-meshheading:17956824-Follow-Up Studies,
pubmed-meshheading:17956824-Humans,
pubmed-meshheading:17956824-Infant,
pubmed-meshheading:17956824-Leukocyte Count,
pubmed-meshheading:17956824-Osteomyelitis,
pubmed-meshheading:17956824-Protein Precursors,
pubmed-meshheading:17956824-Time Factors,
pubmed-meshheading:17956824-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
[Laboratory studies in pediatric bone and joint infections].
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pubmed:affiliation |
Service de Pédiatrie Générale Hôpital Robert Debré, 82, Boulevard Sérurier 75019 Paris, France. mathie.lorrot@rdb.aphp.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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