Source:http://linkedlifedata.com/resource/pubmed/id/17955726
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2007-10-24
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pubmed:abstractText |
HDGC is a hereditary cancer syndrome with an autosomic dominant pattern. It may be clinically diagnosed by family background, and confirmed by genetic testing. In 40% of the families, a mutation in the CDH1 gene (E-cadherin) can be identified. Furthermore, the identification of the pathogenic mutation enables the segregate non-carriers (having population risk) and carriers. Prevention for the latter group includes prophylactic gastrectomy or surveillance endoscopy every 6 to 12 months.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0300-9033
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
158-63
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pubmed:meshHeading |
pubmed-meshheading:17955726-Adenocarcinoma,
pubmed-meshheading:17955726-Adult,
pubmed-meshheading:17955726-Cadherins,
pubmed-meshheading:17955726-Female,
pubmed-meshheading:17955726-Gastrectomy,
pubmed-meshheading:17955726-Genetic Predisposition to Disease,
pubmed-meshheading:17955726-Humans,
pubmed-meshheading:17955726-Mutation,
pubmed-meshheading:17955726-Pedigree,
pubmed-meshheading:17955726-Stomach Neoplasms,
pubmed-meshheading:17955726-Tumor Markers, Biological
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pubmed:year |
2007
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pubmed:articleTitle |
[Hereditary diffuse gastric cancer (HDGC): presentation of a family with a new mutation of the CDH1 gene].
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pubmed:affiliation |
Servicio de Gastroenterología del Hospital Italiano, Cudad Autónoma, Bs As, Argentina. fernandovd04@yahoo.com.ar
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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