Linked Life Data

17917013

Source:http://linkedlifedata.com/resource/pubmed/id/17917013

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
2007-10-5
pubmed:abstractText
Background: Common variable immune deficiency (CVID) is a clinically and immunologically heterogenous primary immune deficiency first described more than 50 years ago. The main features are hypogammaglobulinemia, recurrent infections, and other complications. While CVID is considered as a genetic immune defect, and several genes have been reported as leading to the CVID phenotype, one of the most puzzling features of CVID is the sporadic inheritance pattern and the relatively late onset. In most cases, no other family members have any immune defect. The mean age at diagnosis is between 25 and 45 years of age. These features suggest the interplay between either several or numerous genes with or without potential environmental factors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0257-277X
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
78-86
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Common variable immune deficiency: reviews, continued puzzles, and a new registry.
pubmed:affiliation
Department of Medicine, Mount Sinai Medical Center, The Mount Sinai School of Medicine, New York, NY, USA. Charlotte.Cunningham-Rundles@mssm.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural