Linked Life Data

1791264

Source:http://linkedlifedata.com/resource/pubmed/id/1791264

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-4-1
pubmed:abstractText
The thyrotropin (TSH) and prolactin (PRL) responses to TRH were studied in 15 female depressed patients with melancholia (nine unipolar, six bipolar) during an electroconvulsive therapeutic course. The test was performed before initiation of treatment, 5 days after the final ECT session, and 1 month later, when the patients were on medication with heterocyclic antidepressants (HCAs). The maximal hormonal responses were not altered 5 days after the final ECT but both increased significantly 1 month later. Responders (n = 8) and non-responders (n = 7) to ECT did not differ significantly as regards changes in delta max TSH and PRL. The seven non-responders to ECT improved markedly after 1 month's treatment with HCAs. Three out of four patients with blunted TSH response (less than 5 mu IU/ml) continued to exhibit a blunted response in both post-ECT TRH tests. The rank order of magnitude of delta max TSH remained remarkably stable throughout the assessment period as shown by the highly significant correlations between the values in the three time points.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0165-0327
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-7
pubmed:dateRevised
2009-9-28
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Effects of ECT course on TSH and prolactin responses to TRH in depressed patients.
pubmed:affiliation
Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Greece.
pubmed:publicationType
Journal Article