Linked Life Data

17909371

Source:http://linkedlifedata.com/resource/pubmed/id/17909371

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10 Supl 2
pubmed:dateCreated
2007-10-2
pubmed:abstractText
Studies of patient safety and comparative effectiveness entail unique methodologic challenges. These studies may be susceptible to systematic error, including selection bias, exposure misclassification, and outcome misclassification. They may also be vulnerable to random error, or confounding by a variable such as another drug, a disease, or the drug indication itself. Finally, special logistical issues can arise, including data access problems, difficulties in conveying the need for studies of certain interventions, and obstacles to gaining institutional review board approval. This article provides a conceptual overview of these methodologic issues.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0025-7079
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S13-5
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Methodologic challenges to studying patient safety and comparative effectiveness.
pubmed:affiliation
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. bstrom@cceb.med.upenn.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.