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pubmed:abstractText |
Heritable electrocardiographic (ECG) and heart rate variability (HRV) measures, reflecting pacemaking, conduction, repolarization and autonomic function in the heart have been associated with risks for cardiac arrhythmias. Whereas several rare monogenic conditions with extreme phenotypes have been noted, few common genetic factors contributing to interindividual variability in ECG and HRV measures have been identified. We report the results of a community-based genomewide association study of six ECG and HRV intermediate traits.
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pubmed:affiliation |
The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA. cnewtoncheh@partners.org
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