17901380

Source:http://linkedlifedata.com/resource/pubmed/id/17901380

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001443, umls-concept:C0017260, umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0033640, umls-concept:C0038454, umls-concept:C0815279
pubmed:issue	11
pubmed:dateCreated	2007-10-30
pubmed:abstractText	5' adenosine monophosphate-dependent protein kinase (AMPK) acts as a metabolic sensor. AMPK is elevated under ischemic conditions, but the role of AMPK in ischemic brain remains controversial. In this study, we examined the effects of AMPK inhibition using both pharmacological and genetic approaches in an in vivo stroke model.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/NS050505, http://linkedlifedata.com/resource/pubmed/grant/R01 NS050505-03, http://linkedlifedata.com/resource/pubmed/grant/R01 NS055215-05
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-10098881, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-10716717, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-11602624, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-11665862, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-12511592, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-12546688, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-12838338, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-14573616, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-14688792, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-14729328, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-15028725, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-15058305, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-15689952, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-15772080, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-15846808, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16054041, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16054096, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16260648, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16407220, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16473330, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16518831, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16690704, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16690706, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-16877552, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-17087854, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-17224398, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-17224405, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-8557660, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-8910387, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-9208914, http://linkedlifedata.com/resource/pubmed/commentcorrection/17901380-9693118
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0235266
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/AMP-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Multienzyme Complexes, http://linkedlifedata.com/resource/pubmed/chemical/Neuroprotective Agents, http://linkedlifedata.com/resource/pubmed/chemical/Protein Subunits, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/STK11 protein, human
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1524-4628
pubmed:author	pubmed-author:McCulloughLouise DLD, pubmed-author:MeeSS, pubmed-author:RonnettGabriele VGV, pubmed-author:ViolletBenoitB, pubmed-author:ZengZhiyuanZ
pubmed:issnType	Electronic
pubmed:volume	38
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2992-9
pubmed:dateRevised	2010-9-27
pubmed:meshHeading	pubmed-meshheading:17901380-AMP-Activated Protein Kinases, pubmed-meshheading:17901380-Animals, pubmed-meshheading:17901380-Brain, pubmed-meshheading:17901380-Brain Chemistry, pubmed-meshheading:17901380-Brain Ischemia, pubmed-meshheading:17901380-Cell Death, pubmed-meshheading:17901380-Cytoprotection, pubmed-meshheading:17901380-Disease Models, Animal, pubmed-meshheading:17901380-Dose-Response Relationship, Drug, pubmed-meshheading:17901380-Drug Administration Schedule, pubmed-meshheading:17901380-Enzyme Activation, pubmed-meshheading:17901380-Enzyme Inhibitors, pubmed-meshheading:17901380-Gene Deletion, pubmed-meshheading:17901380-Male, pubmed-meshheading:17901380-Mice, pubmed-meshheading:17901380-Mice, Inbred C57BL, pubmed-meshheading:17901380-Mice, Knockout, pubmed-meshheading:17901380-Multienzyme Complexes, pubmed-meshheading:17901380-Neuroprotective Agents, pubmed-meshheading:17901380-Protein Subunits, pubmed-meshheading:17901380-Protein-Serine-Threonine Kinases, pubmed-meshheading:17901380-Stroke, pubmed-meshheading:17901380-Treatment Outcome
pubmed:year	2007
pubmed:articleTitle	Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke.
pubmed:affiliation	Department of Neurology, University of Connecticut Health Center, Farmington, CT 06030, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural