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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-3-31
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pubmed:abstractText |
Classic coronary heart disease (CHD) risk factors fail to explain the large gradient in CHD incidence between Northern Ireland and France. The Prospective Epidemiological Study of Myocardial Infarction (PRIME) study, a multicentre prospective study of 10,593 middle-aged males, investigated novel risk factors in these populations. We tested the hypotheses that (1) higher paraoxonase activity is associated with decreased CHD risk and (2) PON55 LL genotype is associated with increased CHD risk.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
197
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
556-63
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pubmed:meshHeading |
pubmed-meshheading:17900591-Apolipoprotein A-I,
pubmed-meshheading:17900591-Aryldialkylphosphatase,
pubmed-meshheading:17900591-Case-Control Studies,
pubmed-meshheading:17900591-Coronary Disease,
pubmed-meshheading:17900591-Follow-Up Studies,
pubmed-meshheading:17900591-France,
pubmed-meshheading:17900591-Genetic Predisposition to Disease,
pubmed-meshheading:17900591-Humans,
pubmed-meshheading:17900591-Lipoproteins, HDL,
pubmed-meshheading:17900591-Male,
pubmed-meshheading:17900591-Middle Aged,
pubmed-meshheading:17900591-Northern Ireland,
pubmed-meshheading:17900591-Nutrition Surveys,
pubmed-meshheading:17900591-Polymorphism, Single Nucleotide,
pubmed-meshheading:17900591-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Paraoxonase activity and coronary heart disease risk in healthy middle-aged males: the PRIME study.
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pubmed:affiliation |
Faculty of Medicine, Queen's University Belfast, Belfast, Northern Ireland, UK.
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pubmed:publicationType |
Journal Article,
Multicenter Study
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