|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001407,
umls-concept:C0013227,
umls-concept:C0034493,
umls-concept:C0085979,
umls-concept:C0086466,
umls-concept:C0439596,
umls-concept:C0871161,
umls-concept:C1272883,
umls-concept:C1272936,
umls-concept:C1522223,
umls-concept:C1527240,
umls-concept:C1533685
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2007-10-18
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|
pubmed:abstractText |
The aim of this study was to investigate intraocular properties and determine the highest nontoxic dose of hexadecyloxypropyl-cyclic-HPMPA (HDP-cHPMPA), a novel, potent, intravitreally injectable, slow-releasing crystalline drug for long-acting treatment of cytomegalovirus (CMV) retinitis.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1080-7683
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
433-44
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pubmed:meshHeading |
pubmed-meshheading:17900229-Adenine,
pubmed-meshheading:17900229-Animals,
pubmed-meshheading:17900229-Antiviral Agents,
pubmed-meshheading:17900229-Cell Line,
pubmed-meshheading:17900229-Cytomegalovirus,
pubmed-meshheading:17900229-Cytomegalovirus Retinitis,
pubmed-meshheading:17900229-Delayed-Action Preparations,
pubmed-meshheading:17900229-Electroretinography,
pubmed-meshheading:17900229-Eye,
pubmed-meshheading:17900229-Fibroblasts,
pubmed-meshheading:17900229-Guinea Pigs,
pubmed-meshheading:17900229-Injections,
pubmed-meshheading:17900229-Intraocular Pressure,
pubmed-meshheading:17900229-Organophosphorus Compounds,
pubmed-meshheading:17900229-Rabbits,
pubmed-meshheading:17900229-Vitreous Body
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Intraocular properties of an alkoxyalkyl derivative of cyclic 9-(S)-(3-hydroxyl-2-phosphonomehoxypropyl) adenine, an intravitreally injectable anti-HCMV drug in rabbit and guinea pig.
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|
pubmed:affiliation |
Jacobs Retina Center at Shiley Eye Center, University of California-San Diego Department of Ophthalmology, La Jolla, San Diego, CA 92037, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
