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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-10-24
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pubmed:abstractText |
Recent studies indicate transcription factor hepatocyte nuclear factor 4 alpha (HNF-4 alpha, HNF4A) modulates the transcription of the pancreatic B-cell ATP-sensitive K+ (KATP) channel subunit Kir6.2 gene (KCNJ11). Both HNF4A and KCNJ11 have previously been associated with diabetes risk but little is known whether the variations in these genes interact with each other.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0742-3071
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1187-91
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17894829-Adult,
pubmed-meshheading:17894829-Case-Control Studies,
pubmed-meshheading:17894829-Diabetes Mellitus, Type 2,
pubmed-meshheading:17894829-Female,
pubmed-meshheading:17894829-Genetic Variation,
pubmed-meshheading:17894829-Genotype,
pubmed-meshheading:17894829-Hepatocyte Nuclear Factor 4,
pubmed-meshheading:17894829-Humans,
pubmed-meshheading:17894829-Middle Aged,
pubmed-meshheading:17894829-Polymorphism, Genetic,
pubmed-meshheading:17894829-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:17894829-Predictive Value of Tests,
pubmed-meshheading:17894829-Prospective Studies
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pubmed:year |
2007
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pubmed:articleTitle |
Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women.
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pubmed:affiliation |
Department of Nutrition, Harvard Medical School of Public Health, Boston, MA 02115, USA. nhlqi@channing.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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