Linked Life Data

17892941

Source:http://linkedlifedata.com/resource/pubmed/id/17892941

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pubmed-article:17892941pubmed:abstractTextIn a previous work our group showed that some synthetic stigmastanes may play a role in immune-mediated inflammation. In this paper we report the syntheses of a series of new steroidal compounds derived from dehydroepiandrosterone and stigmasterol, and the evaluation of their in vitro inhibitory activity of the TNF-alpha production by macrophages. A preliminary qualitative structure-activity relationship was established.lld:pubmed
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pubmed-article:17892941pubmed:year2007lld:pubmed
pubmed-article:17892941pubmed:articleTitleSyntheses of immunomodulating androstanes and stigmastanes: comparison of their TNF-alpha inhibitory activity.lld:pubmed
pubmed-article:17892941pubmed:affiliationDepartamento de Química Orgánica and UMYMFOR (CONICET-Facultad de Ciencias Exactas y Naturales), Universidad de Buenos Aires, Pabellón 2, Piso 3, Ciudad Universitaria, C1428EGA, Buenos Aires, Argentina.lld:pubmed
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pubmed-article:17892941pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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