|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2008-8-14
|
|
pubmed:abstractText |
Nasopharyngeal cancer (NPC) is a multi-factorial disease, and the genetic background may be a crucial etiologic factor. The xeroderma pigmentosum complementation group C (XPC) is mainly involved in DNA damage repair, and the sequence variants in XPC gene may modulate DNA repair capacity and consequently lead to an individual's susceptibility to NPC. The aims of this study were to examine the association between XPC Val499Ala, Lys939Gln, PAT polymorphisms and the genetic susceptibility of nasopharyngeal carcinoma (NPC) in Chinese population.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1651-226X
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
47
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
379-84
|
|
pubmed:dateRevised |
2009-5-12
|
|
pubmed:meshHeading |
pubmed-meshheading:17882560-Adult,
pubmed-meshheading:17882560-Alleles,
pubmed-meshheading:17882560-Amino Acid Substitution,
pubmed-meshheading:17882560-Carcinoma,
pubmed-meshheading:17882560-Case-Control Studies,
pubmed-meshheading:17882560-China,
pubmed-meshheading:17882560-Cocarcinogenesis,
pubmed-meshheading:17882560-DNA-Binding Proteins,
pubmed-meshheading:17882560-Female,
pubmed-meshheading:17882560-Genetic Predisposition to Disease,
pubmed-meshheading:17882560-Genotype,
pubmed-meshheading:17882560-Haplotypes,
pubmed-meshheading:17882560-Humans,
pubmed-meshheading:17882560-Male,
pubmed-meshheading:17882560-Middle Aged,
pubmed-meshheading:17882560-Mutation, Missense,
pubmed-meshheading:17882560-Nasopharyngeal Neoplasms,
pubmed-meshheading:17882560-Point Mutation,
pubmed-meshheading:17882560-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17882560-Risk,
pubmed-meshheading:17882560-Smoking
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
The xeroderma pigmentosum group C gene polymorphisms and genetic susceptibility of nasopharyngeal carcinoma.
|
|
pubmed:affiliation |
Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
