Linked Life Data

17881089

Source:http://linkedlifedata.com/resource/pubmed/id/17881089

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2007-12-17
pubmed:abstractText
Brain functions such as information processing, learning and memory are commonly associated with changes in synaptic strength, the synaptic plasticity. Extrasynaptic diffusion of transmitters thought to mediate only a modulatory effect. Here I suggest a hypothesis that concentration profile of signaling molecules in the extracellular space can form a "diffuse guiding template" for signal propagation through neuronal network. Such template can be potentially involved in information processing and storage. This hypothesis requires further experimental investigation and, thus, provides a framework for future studies in the field of non-synaptic transmission in the brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0197-0186
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-3
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Can diffuse extrasynaptic signaling form a guiding template?
pubmed:affiliation
RIKEN Brain Science Institute (BSI), Neuronal Circuit Mechanisms Research Group, Semyanov Research Unit, Japan. semyanov@brain.riken.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't