Linked Life Data

17878326

Source:http://linkedlifedata.com/resource/pubmed/id/17878326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2007-9-19
pubmed:abstractText
A provocative study has shown that viral peptides may be transferred in vitro from epithelial cells to APC through connexin-43 gap junction channels. In support of this cross-presentation pathway, the study also reported that human dendritic cells, including Langerhans cells of skin, express connexin-43. In this report we show that if this was the case, the levels of connexin-43 are below those detectable by immunofluorescence, flow cytometry, quantitative PCR of purified CD1a+ cells, and electron microscopy, raising questions about the relevance of the connexin-43-dependent mechanism for Langerhans cells of noninflamed human skin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-1767
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
179
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4318-21
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Cutting edge: Lack of evidence for connexin-43 expression in human epidermal Langerhans cells.
pubmed:affiliation
Division of Immunology and Allergy, Department of Internal Medicine, Geneva University Hospitals and Medical School, Switzerland. Simone.Zimmerli@hcuge.ch
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't