Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-3-24
pubmed:abstractText
Neuroimaging studies of behavioral-induced anxiety in non-patients and of lactate-induced anxiety in panic disorder patients have indicated that normal and pathological anxiety may share a common pathway involving the temporal poles. As panic-related anxiety may reflect faulty temporopolar evaluative processing of input, the objective of this study was to examine sensory reactivity in panic disorder patients via scalp recordings of the late auditory evoked 'vertex' potential (LAEP) which appears to have a predominantly temporal lobe origin. Twelve patients diagnosed according to DSM-III criteria as panic disorder and ten normal controls served as subjects in this study. EEG was recorded from 16 scalp sites using a monopolar fronto-occipital derivation and LAEPs were separately averaged in response to four acoustic intensities. Analysis focused on group and electrode-site differences in the negative (N1) and positive (P2) component amplitudes of the LAEPs. Panic disorder patients were found to exhibit significantly larger N1 amplitudes across all stimulus intensities and across all recording sites. No significant group differences were observed with P2. Although the results provide indirect support for a temporal focus, other modulating influences must be considered in data interpretation.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-14889304, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2293250, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2302439, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2411518, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2643361, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2764179, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2784226, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2786401, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2901741, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-2913974, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-3290994, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-3485385, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-3574642, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-3741311, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-4129630, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-57046, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-57047, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6159179, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6171630, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6172256, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6181984, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6332277, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6370083, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6588891, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6718651, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-6742977, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-7117475, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-7174905, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-7339642, http://linkedlifedata.com/resource/pubmed/commentcorrection/1786264-824022
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1180-4882
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-20
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Auditory evoked potentials in panic disorder.
pubmed:affiliation
Institute of Mental Health Research/Department of Psychiatry and Psychology, University of Ottawa, Ontario.
pubmed:publicationType
Journal Article