rdf:type |
|
lifeskim:mentions |
umls-concept:C0003289,
umls-concept:C0015215,
umls-concept:C0030705,
umls-concept:C0178733,
umls-concept:C0205210,
umls-concept:C0439857,
umls-concept:C0443199,
umls-concept:C0599861,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1269683,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
8
|
pubmed:dateCreated |
2007-9-14
|
pubmed:abstractText |
Predictors of treatment response to serotonergic versus nonserotonergic, e.g., noradrenergic, antidepressants are of considerable clinical relevance as they could help to reduce the occurrence of patients' receiving weeks or even months of unsuccessful treatment. Several studies show that the response to selective serotonin reuptake inhibitors can be successfully predicted by using the loudness dependence of auditory evoked potentials (LDAEP), which denotes change in the amplitudes in response to different stimulus intensities and is to date one of the best validated indicators of the central serotonergic system. The aim of the current randomized prospective study was to investigate whether or not LDAEP also allows the differential prediction of treatment response to serotonergic versus noradrenergic antidepressants.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1555-2101
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
68
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1206-12
|
pubmed:meshHeading |
pubmed-meshheading:17854244-Adrenergic Uptake Inhibitors,
pubmed-meshheading:17854244-Adult,
pubmed-meshheading:17854244-Analysis of Variance,
pubmed-meshheading:17854244-Antipsychotic Agents,
pubmed-meshheading:17854244-Citalopram,
pubmed-meshheading:17854244-Depressive Disorder, Major,
pubmed-meshheading:17854244-Drug Therapy, Combination,
pubmed-meshheading:17854244-Evoked Potentials, Auditory,
pubmed-meshheading:17854244-Female,
pubmed-meshheading:17854244-Humans,
pubmed-meshheading:17854244-Male,
pubmed-meshheading:17854244-Morpholines,
pubmed-meshheading:17854244-Prospective Studies,
pubmed-meshheading:17854244-Serotonin Uptake Inhibitors,
pubmed-meshheading:17854244-Treatment Outcome
|
pubmed:year |
2007
|
pubmed:articleTitle |
Differential prediction of first clinical response to serotonergic and noradrenergic antidepressants using the loudness dependence of auditory evoked potentials in patients with major depressive disorder.
|
pubmed:affiliation |
Department of Psychiatry, Ruhr-University Bochum, Bochum, Germany. juckelgwk@aol.com
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|