Source:http://linkedlifedata.com/resource/pubmed/id/17851665
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2008-2-4
|
| pubmed:abstractText |
To implement a high-resolution first-pass myocardial perfusion imaging protocol (HRPI) at 3 T, and to evaluate the feasibility, image quality and accuracy of this approach prospectively in patients with suspected CAD. We hypothesized that utilizing the gain in SNR at 3 T to increase spatial resolution would reduce partial volume effects and subendocardial dark rim artifacts in comparison to 1.5 T. HRPI studies were performed on 60 patients using a segmented k-space gradient echo sequence (in plane resolution 1.97 x 1.94 mm(2)). Semiquantitative assessment of dark rim artifacts was performed for the stress studies on a slice-by-slice basis. Qualitative visual analysis was compared to quantitative coronary angiography (QCA) results; hemodynamically significant CAD was defined as stenosis >or=70% at QCA. Dark rim artifacts appeared in 108 of 180 slices (average extent 1.3 +/- 1.2 mm representing 11.8 +/- 10.8% of the transmural myocardial thickness). Sensitivity, specifity, and test accuracy for the detection of significant CAD were 89%,79%, and 85%. HRPI studies at 3 T are feasible in a clinical setting, providing good image quality and high accuracy for detection of significant CAD. The presence of dark rim artifacts does not appear to represent a diagnostic problem when using a HRPI approach.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0938-7994
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
18
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
226-33
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| pubmed:meshHeading |
pubmed-meshheading:17851665-Adult,
pubmed-meshheading:17851665-Aged,
pubmed-meshheading:17851665-Artifacts,
pubmed-meshheading:17851665-Contrast Media,
pubmed-meshheading:17851665-Coronary Angiography,
pubmed-meshheading:17851665-Coronary Artery Disease,
pubmed-meshheading:17851665-Coronary Stenosis,
pubmed-meshheading:17851665-Feasibility Studies,
pubmed-meshheading:17851665-Female,
pubmed-meshheading:17851665-Humans,
pubmed-meshheading:17851665-Image Enhancement,
pubmed-meshheading:17851665-Magnetic Resonance Angiography,
pubmed-meshheading:17851665-Magnetic Resonance Imaging,
pubmed-meshheading:17851665-Magnetics,
pubmed-meshheading:17851665-Male,
pubmed-meshheading:17851665-Middle Aged,
pubmed-meshheading:17851665-Myocardium,
pubmed-meshheading:17851665-Observer Variation,
pubmed-meshheading:17851665-Organometallic Compounds,
pubmed-meshheading:17851665-Prospective Studies,
pubmed-meshheading:17851665-Reproducibility of Results,
pubmed-meshheading:17851665-Sensitivity and Specificity
|
| pubmed:year |
2008
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| pubmed:articleTitle |
High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery disease.
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| pubmed:affiliation |
Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53129, Bonn, Germany.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Controlled Clinical Trial
|