Source:http://linkedlifedata.com/resource/pubmed/id/17850999
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2007-10-9
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pubmed:abstractText |
Bilateral cochlear implants aim to restore binaural processing along the auditory pathways in children with bilateral deafness. We assessed auditory brainstem activity evoked by single biphasic pulses delivered by an apical or basal electrode from the left, right and both cochlear implants in 13 children. Repeated measures were made over the first 9-30 months of bilateral implant use. In children with short or long periods of unilateral implant use prior to the second implantation, Wave eV of the auditory brainstem response was initially prolonged when evoked by the naïve versus experienced side. These differences tended to resolve in children first implanted <3 years of age but not in children implanted at older ages with long delays between implants. Latency differences were projected to persist for longer periods in children with long delays between implants compared with children with short delays. No differences in right versus left evoked eV latency were found in 2 children receiving bilateral implants simultaneously and their response latencies decreased over time. Binaural interaction responses showed effects of stimulating electrode position (responses were more detectable when evoked by an apical than basal pair of implant electrodes), and duration of delay between implants (measured by latency delays). The trends shown here suggest a negative impact of unilateral implant use on bilateral auditory brainstem plasticity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0378-5955
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
233
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-107
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pubmed:meshHeading |
pubmed-meshheading:17850999-Auditory Pathways,
pubmed-meshheading:17850999-Brain Stem,
pubmed-meshheading:17850999-Child, Preschool,
pubmed-meshheading:17850999-Cochlear Implantation,
pubmed-meshheading:17850999-Cochlear Implants,
pubmed-meshheading:17850999-Deafness,
pubmed-meshheading:17850999-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:17850999-Humans,
pubmed-meshheading:17850999-Infant,
pubmed-meshheading:17850999-Neuronal Plasticity,
pubmed-meshheading:17850999-Reaction Time,
pubmed-meshheading:17850999-Time Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Auditory brainstem activity in children with 9-30 months of bilateral cochlear implant use.
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pubmed:affiliation |
Cochlear Implant Laboratory, The Hospital for Sick Children, Room 6D08, 555 University Avenue, Toronto, ON, Canada M5G 1X8. karen.gordon@utoronto.ac
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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