Linked Life Data

17850633

Source:http://linkedlifedata.com/resource/pubmed/id/17850633

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-9-13
pubmed:abstractText
Gaucher disease (GD) is a lysosomal storage disorder with a wide spectrum of phenotypic presentations. We report the case histories of two adult brothers with GD who developed both parkinsonism and psychiatric symptoms. Direct sequencing and real-time polymerase chain reaction were used to establish that the patients were homozygous for mutation L444P. While parkinsonism has been described previously in GD, these patients had atypical features, including a complicated mood disorder. The comorbidity of GD and a mood disorder is a new finding, as psychiatric manifestations of GD have been described rarely. The etiology of the mental illness could be related to the processes contributing to the development of parkinsonism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0009-9163
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-61
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Movement and mood disorder in two brothers with Gaucher disease.
pubmed:affiliation
Servizio Psichiatrico di Diagnosi e Cura, Ospedale Santo Spirito, Rome, Italy.
pubmed:publicationType
Journal Article, Case Reports, Research Support, N.I.H., Intramural