Linked Life Data

17827965

Source:http://linkedlifedata.com/resource/pubmed/id/17827965

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-11-28
pubmed:abstractText
The purpose of this study is to assess the efficacy and the tolerability of a new vision-based non-intrusive eye tracker in a population composed of normal controls and in patients affected by nonadvanced Parkinson's disease (PD). PD patients characteristically have difficulty in sustaining repetitive motor actions. Previous studies showed a progressive bradykinesia and hypokinesia of pursuit ocular movements (POM) in advanced PD. We found that the values of POM were lower in PD patients than in normal controls (p < 0.001). In PD patients, the values correlated closely with Hoehn and Yahr stage and Unified Parkinson Disease Rating Scale motor subscore (p < 0.001, for both). Our data suggest that deficit in POM occurs also in nonadvanced PD patients and it is closely correlated with clinical scores. Thus, this vision-based system can be considered a new method to provide, noninvasively, measures of POM dysfunctions and can be used as reliable indices of disease severity in PD patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1421-9913
pubmed:author
pubmed:copyrightInfo
(c) 2007 S. Karger AG, Basel.
pubmed:issnType
Electronic
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-7
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Quantitative analysis of pursuit ocular movements in Parkinson's disease by using a video-based eye tracking system.
pubmed:affiliation
IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy. marino@centroneurolesi.it
pubmed:publicationType
Journal Article