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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2007-11-21
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pubmed:abstractText |
On-pump coronary artery bypass graft (CABG) surgery triggers an inflammatory response (IR) which may impair revascularization. The study aimed at (1) characterizing the temporal profile of the IR by assaying appropriate markers in both systemic and coronary blood, and (2) determining whether (and which doses of) cardiovascular drugs known to have antiinflammatory properties, namely statins and ACE-inhibitors (ACEI), inhibit the response.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Creatine Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/E-Selectin,
http://linkedlifedata.com/resource/pubmed/chemical/Enalapril,
http://linkedlifedata.com/resource/pubmed/chemical/Heptanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/IL6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Ramipril,
http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Cell Adhesion Molecule-1,
http://linkedlifedata.com/resource/pubmed/chemical/atorvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/von Willebrand Factor
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:AzzellinoAriannaA,
pubmed-author:BalestriGiuliaG,
pubmed-author:CazzanigaMariaM,
pubmed-author:CerritoM GraziaMG,
pubmed-author:CusaElena NegroEN,
pubmed-author:DeCarliniCaterinaC,
pubmed-author:FerrariAlberto UAU,
pubmed-author:GarducciStefanoS,
pubmed-author:GuerraLucaL,
pubmed-author:LavitranoMaria LuisaML,
pubmed-author:LoardiClaudiaC,
pubmed-author:ManciaGiuseppeG,
pubmed-author:MenicantiLorenzoL,
pubmed-author:PaoliniGiovanniG,
pubmed-author:RadaelliAlbertoA,
pubmed-author:SantoDaniloD
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2750-5
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pubmed:meshHeading |
pubmed-meshheading:17823365-Aged,
pubmed-meshheading:17823365-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:17823365-Anti-Inflammatory Agents,
pubmed-meshheading:17823365-Coronary Artery Bypass,
pubmed-meshheading:17823365-Coronary Artery Disease,
pubmed-meshheading:17823365-Coronary Circulation,
pubmed-meshheading:17823365-Creatine Kinase,
pubmed-meshheading:17823365-Dose-Response Relationship, Drug,
pubmed-meshheading:17823365-E-Selectin,
pubmed-meshheading:17823365-Enalapril,
pubmed-meshheading:17823365-Female,
pubmed-meshheading:17823365-Heptanoic Acids,
pubmed-meshheading:17823365-Humans,
pubmed-meshheading:17823365-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:17823365-Inflammation,
pubmed-meshheading:17823365-Inflammation Mediators,
pubmed-meshheading:17823365-Interleukin-6,
pubmed-meshheading:17823365-Leukocyte Count,
pubmed-meshheading:17823365-Male,
pubmed-meshheading:17823365-Middle Aged,
pubmed-meshheading:17823365-Platelet Count,
pubmed-meshheading:17823365-Pyrroles,
pubmed-meshheading:17823365-Ramipril,
pubmed-meshheading:17823365-Simvastatin,
pubmed-meshheading:17823365-Stroke Volume,
pubmed-meshheading:17823365-Time Factors,
pubmed-meshheading:17823365-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:17823365-Treatment Outcome,
pubmed-meshheading:17823365-Tumor Necrosis Factor-alpha,
pubmed-meshheading:17823365-Vascular Cell Adhesion Molecule-1,
pubmed-meshheading:17823365-von Willebrand Factor
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pubmed:year |
2007
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pubmed:articleTitle |
Inflammatory activation during coronary artery surgery and its dose-dependent modulation by statin/ACE-inhibitor combination.
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pubmed:affiliation |
Divisione di Riabilitazione Cardiologica - Ospedale San Gerardo, Via Pergolesi, 33, 20052 Monza, Italy.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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