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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-5-29
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pubmed:abstractText |
Studies of hypothalamic-pituitary-adrenal (HPA) axis function in chronic fatigue syndrome (CFS) point to hypofunction, although there are negative reports. Suggested mechanisms include a reduced hypothalamic or supra-hypothalamic stimulus to the HPA axis and enhanced sensitivity to the negative feedback of glucocorticoids. The aim of the current study was to investigate HPA axis function in CFS with the dexamethasone/corticotropin-releasing factor (Dex/CRF) test, in analogy with research in affective disorders.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0033-2917
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
963-73
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pubmed:meshHeading |
pubmed-meshheading:17803834-Adrenal Cortex,
pubmed-meshheading:17803834-Adrenal Cortex Function Tests,
pubmed-meshheading:17803834-Adult,
pubmed-meshheading:17803834-Case-Control Studies,
pubmed-meshheading:17803834-Corticotropin-Releasing Hormone,
pubmed-meshheading:17803834-Depressive Disorder, Major,
pubmed-meshheading:17803834-Dexamethasone,
pubmed-meshheading:17803834-Fatigue Syndrome, Chronic,
pubmed-meshheading:17803834-Female,
pubmed-meshheading:17803834-Glucocorticoids,
pubmed-meshheading:17803834-Hormones,
pubmed-meshheading:17803834-Humans,
pubmed-meshheading:17803834-Hypothalamo-Hypophyseal System,
pubmed-meshheading:17803834-Pituitary-Adrenal System,
pubmed-meshheading:17803834-Saliva,
pubmed-meshheading:17803834-Stress, Psychological
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pubmed:year |
2008
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pubmed:articleTitle |
Combined dexamethasone/corticotropin-releasing factor test in chronic fatigue syndrome.
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pubmed:affiliation |
Department of Psychiatry, Antwerp University Hospital, Edegem, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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