Linked Life Data

17764187

Source:http://linkedlifedata.com/resource/pubmed/id/17764187

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2007-9-20
pubmed:abstractText
Described is an efficient synthesis of silyl-substituted salen ligands, used for the preparation of enantioselective catalysts. The salicylaldehyde precursors are synthesized from the silyl ethers of 2,6-dibromophenols via a one-pot double lithium halogen exchanges, to induce an intramolecular retro-Brook rearrangement and allow introduction of the aldehyde group. Condensation of the salicylaldehyde products with a chiral diamine affords the silyl-substituted salen ligands in high yields. The use of other electrophiles allows easy access to silyl-substituted phenolic esters, ketones, and boronic acids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1523-7060
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3873-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Expedient, high-yielding synthesis of silyl-substituted salen ligands.
pubmed:affiliation
Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural