rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1-2
|
pubmed:dateCreated |
2007-9-24
|
pubmed:abstractText |
The haem-binding protein alpha(1)-microglobulin (alpha(1)m) is involved in protection against oxidative damage induced by extracellular haem/haemoglobin. A carboxy-terminally truncated form of alpha(1)m (t-alpha(1)m), formed by reactions with haemoglobin, degrades haem into a yellow-brown chromophore linked to the protein. The aim of this work was to investigate if t-alpha(1)m is present in urine from a large cohort and if urinary and plasma alpha(1)m/t-alpha(1)m concentrations are changed in patients with haemolytic disorders and haemochromatosis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0009-8981
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
386
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
31-7
|
pubmed:meshHeading |
pubmed-meshheading:17706626-Alpha-Globulins,
pubmed-meshheading:17706626-Biological Markers,
pubmed-meshheading:17706626-Blotting, Western,
pubmed-meshheading:17706626-Case-Control Studies,
pubmed-meshheading:17706626-Creatinine,
pubmed-meshheading:17706626-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:17706626-Female,
pubmed-meshheading:17706626-Hematologic Diseases,
pubmed-meshheading:17706626-Hemochromatosis,
pubmed-meshheading:17706626-Humans,
pubmed-meshheading:17706626-Kidney Glomerulus,
pubmed-meshheading:17706626-Male,
pubmed-meshheading:17706626-Radioimmunoassay,
pubmed-meshheading:17706626-beta 2-Microglobulin
|
pubmed:articleTitle |
Quantitative and qualitative evaluation of plasma and urine alpha1-microglobulin in healthy donors and patients with different haemolytic disorders and haemochromatosis.
|
pubmed:affiliation |
Department of Clinical Sciences Lund University, Sweden.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|