rdf:type |
|
lifeskim:mentions |
umls-concept:C0006610,
umls-concept:C0024501,
umls-concept:C0087111,
umls-concept:C0205197,
umls-concept:C0205210,
umls-concept:C0205225,
umls-concept:C0449258,
umls-concept:C0871261,
umls-concept:C1140680,
umls-concept:C1516213,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1710082,
umls-concept:C2347296,
umls-concept:C2911692
|
pubmed:issue |
24
|
pubmed:dateCreated |
2007-8-20
|
pubmed:abstractText |
For ovarian cancer patients receiving maintenance treatment after complete clinical response to primary therapy, we tested the predictive value of the following early signal of progressive disease (EPD) criterion based on serum CA-125: for patients with CA-125 nadir <or= 10 U/mL, a confirmed value of >or= 20 U/mL serves as an early signal of CA-125 progression; for patients with nadir more than 10 U/mL, a value >or= 2x nadir that is confirmed predicts progression. PATIENTS AND METHODS The EPD criterion was tested on Southwest Oncology Group trial 9701/Gynecologic Oncology Group trial 178 patients (n = 288) and compared with Gynecologic Cancer Intergroup criterion.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1527-7755
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
20
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3615-20
|
pubmed:dateRevised |
2007-12-3
|
pubmed:meshHeading |
pubmed-meshheading:17704410-Aged,
pubmed-meshheading:17704410-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:17704410-CA-125 Antigen,
pubmed-meshheading:17704410-Disease Progression,
pubmed-meshheading:17704410-False Positive Reactions,
pubmed-meshheading:17704410-Female,
pubmed-meshheading:17704410-Humans,
pubmed-meshheading:17704410-Middle Aged,
pubmed-meshheading:17704410-Ovarian Neoplasms,
pubmed-meshheading:17704410-Prognosis,
pubmed-meshheading:17704410-Tumor Markers, Biological
|
pubmed:year |
2007
|
pubmed:articleTitle |
An early signal of CA-125 progression for ovarian cancer patients receiving maintenance treatment after complete clinical response to primary therapy.
|
pubmed:affiliation |
Southwest Oncology Group Statistical Center, Seattle, WA, USA. pubs@swog.org
|
pubmed:publicationType |
Journal Article,
Comment,
Research Support, N.I.H., Extramural
|