rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-8-16
|
pubmed:abstractText |
Neovascular glaucoma is a secondary glaucoma with grave prognosis which follows ischemic retinal disorders in the majority of cases. Mediators that induce new vessel formation such as the vascular endothelial growth factor-A seem to play a key role in the pathophysiology of this condition. Herein, we report 2 cases with neovascular glaucoma secondary to ischemic central retinal vein occlusion who received treatment with intravitreal bevacizumab (Avastin) a nonselective antibody against vascular endothelial growth factor-A. Both patients demonstrated dramatic short-term response in terms of intraocular pressure reduction and regression of neovascularization.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1057-0829
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
437-9
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:17700285-Angiogenesis Inhibitors,
pubmed-meshheading:17700285-Antibodies, Monoclonal,
pubmed-meshheading:17700285-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:17700285-Glaucoma, Neovascular,
pubmed-meshheading:17700285-Humans,
pubmed-meshheading:17700285-Injections,
pubmed-meshheading:17700285-Intraocular Pressure,
pubmed-meshheading:17700285-Male,
pubmed-meshheading:17700285-Middle Aged,
pubmed-meshheading:17700285-Retinal Vein Occlusion,
pubmed-meshheading:17700285-Treatment Outcome,
pubmed-meshheading:17700285-Vascular Endothelial Growth Factor A,
pubmed-meshheading:17700285-Visual Acuity,
pubmed-meshheading:17700285-Vitreous Body
|
pubmed:year |
2007
|
pubmed:articleTitle |
Intravitreal bevacizumab (Avastin) injection for neovascular glaucoma.
|
pubmed:affiliation |
Ophthalmic Research Center and Department of Ophthalmology, Labbafinejad Medical Center, Shaheed Beheshti Medical University, Tehran, Iran. shahinyazdani@yahoo.com
|
pubmed:publicationType |
Journal Article,
Case Reports
|