Source:http://linkedlifedata.com/resource/pubmed/id/17700253
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
A recent analysis indicates that the excess odds ratio for lung cancer by smoking is described by a function that is linear in pack-years and exponential in the logarithm of smoking intensity and its square (Cancer Epidemiol Biomarkers Prev. 2006;15:517-523). The model suggests that below 15-20 cigarettes per day there is a "direct exposure rate" effect, ie, the excess odds ratio per pack-year for higher intensity (and shorter duration) smokers is greater than for lower-intensity (and longer duration) smokers. Above 20 cigarettes per day, there is an "inverse-exposure-rate" effect, ie, the excess odds ratio per pack-year for higher intensity smokers is smaller than for lower-intensity smokers.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1044-3983
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
639-48
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17700253-Adult,
pubmed-meshheading:17700253-Age Factors,
pubmed-meshheading:17700253-Aged,
pubmed-meshheading:17700253-Case-Control Studies,
pubmed-meshheading:17700253-Data Interpretation, Statistical,
pubmed-meshheading:17700253-Effect Modifier, Epidemiologic,
pubmed-meshheading:17700253-Europe,
pubmed-meshheading:17700253-Female,
pubmed-meshheading:17700253-Humans,
pubmed-meshheading:17700253-Lung Neoplasms,
pubmed-meshheading:17700253-Male,
pubmed-meshheading:17700253-Middle Aged,
pubmed-meshheading:17700253-Models, Statistical,
pubmed-meshheading:17700253-Odds Ratio,
pubmed-meshheading:17700253-Risk Assessment,
pubmed-meshheading:17700253-Smoking,
pubmed-meshheading:17700253-Smoking Cessation
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pubmed:year |
2007
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pubmed:articleTitle |
Cigarette smoking and lung cancer: modeling effect modification of total exposure and intensity.
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pubmed:affiliation |
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA. lubinj@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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