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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
Incidence and mortality rates for renal cell carcinoma (RCC) have been rising for decades. Unfortunately, the molecular events that support RCC carcinogenesis remain poorly understood. In an effort to gain a better understanding of signaling events in clear cell RCC (cRCC), we investigated the antitumor activity of secreted frizzled-related protein 1 (sFRP1), a negative regulator of Wnt signaling.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AhlquistDavid ADA,
pubmed-author:BelmonteLeandra SLS,
pubmed-author:ChildsApril CAC,
pubmed-author:CoplandJohn AJA,
pubmed-author:GumzMichelle LML,
pubmed-author:KreinestPamela APA,
pubmed-author:LeGrandShauna NSN,
pubmed-author:LuxonBruce ABA,
pubmed-author:ParkerAlexander SAS,
pubmed-author:RaoM HMH,
pubmed-author:SinhaMalaM,
pubmed-author:WoodChristopher GCG,
pubmed-author:WuKevin JKJ,
pubmed-author:ZouHongzhiH
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4740-9
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17699851-Animals,
pubmed-meshheading:17699851-Carcinoma, Renal Cell,
pubmed-meshheading:17699851-Cell Line, Tumor,
pubmed-meshheading:17699851-Cell Proliferation,
pubmed-meshheading:17699851-DNA Methylation,
pubmed-meshheading:17699851-Female,
pubmed-meshheading:17699851-Glycoproteins,
pubmed-meshheading:17699851-Humans,
pubmed-meshheading:17699851-Kidney Neoplasms,
pubmed-meshheading:17699851-Mice,
pubmed-meshheading:17699851-Phenotype,
pubmed-meshheading:17699851-Signal Transduction,
pubmed-meshheading:17699851-Tumor Suppressor Proteins,
pubmed-meshheading:17699851-Wnt Proteins
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pubmed:year |
2007
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pubmed:articleTitle |
Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma.
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pubmed:affiliation |
Department of Cancer Biology, Mayo Clinic Jacksonville, Florida 32224, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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