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pubmed-article:17696965pubmed:abstractTextInflammatory and/or immune activation occurs both in animal models (twitcher mice) and in the brain of patients with Globoid cell leukodystrophy (GLD) or Krabbe's disease (KD). In this study we evaluated in vitro the cytokine profile of KD patients and the effect of psychosine, the toxic metabolite which plays a role in the demyelination process in these patients.lld:pubmed
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pubmed-article:17696965pubmed:authorpubmed-author:Di RenzoMMlld:pubmed
pubmed-article:17696965pubmed:authorpubmed-author:PasquiA LALlld:pubmed
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pubmed-article:17696965pubmed:articleTitleIncreased TNF-alpha production by peripheral blood mononuclear cells in patients with Krabbe's disease: effect of psychosine.lld:pubmed
pubmed-article:17696965pubmed:affiliationUniversity of Siena, Italy. pasquian@unisi.itlld:pubmed
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pubmed-article:17696965pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed