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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
Inflammatory and/or immune activation occurs both in animal models (twitcher mice) and in the brain of patients with Globoid cell leukodystrophy (GLD) or Krabbe's disease (KD). In this study we evaluated in vitro the cytokine profile of KD patients and the effect of psychosine, the toxic metabolite which plays a role in the demyelination process in these patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-2972
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
742-5
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pubmed:dateRevised |
2008-6-25
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pubmed:meshHeading |
pubmed-meshheading:17696965-Adult,
pubmed-meshheading:17696965-Animals,
pubmed-meshheading:17696965-Cytokines,
pubmed-meshheading:17696965-Disease Models, Animal,
pubmed-meshheading:17696965-Female,
pubmed-meshheading:17696965-Humans,
pubmed-meshheading:17696965-Leukodystrophy, Globoid Cell,
pubmed-meshheading:17696965-Male,
pubmed-meshheading:17696965-Mice,
pubmed-meshheading:17696965-Psychosine,
pubmed-meshheading:17696965-Treatment Outcome,
pubmed-meshheading:17696965-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Increased TNF-alpha production by peripheral blood mononuclear cells in patients with Krabbe's disease: effect of psychosine.
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pubmed:affiliation |
University of Siena, Italy. pasquian@unisi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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