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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-8-10
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pubmed:abstractText |
We evaluated 3 new markers for coronary artery disease (CAD) [bilirubin, total homocysteine (t-Hcy) and high-sensitivity C-reactive protein (hs-CRP)] in 319 patients with chest pains divided into 2 groups based on coronary angiography: CAD group (n = 262) and non-CAD group (n = 57). A control group consisted of 50 healthy subjects. t-Hcy had the highest diagnostic value for diagnosis of angiographically documented patients; bilirubin had the lowest. The sensitivities and specificities (based on ROC curves) of bilirubin, hs-CRP and t-Hcy were 70.9%, 50% and 76.8% respectively, and 40.4%, 80.7% and 70.2% respectively. We conclude that serum bilirubin levels cannot identify people at risk of CAD and t-Hcy and hs-CRP may be stronger markers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1020-3397
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
522-35
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17687824-Analysis of Variance,
pubmed-meshheading:17687824-Area Under Curve,
pubmed-meshheading:17687824-Bilirubin,
pubmed-meshheading:17687824-Biological Markers,
pubmed-meshheading:17687824-C-Reactive Protein,
pubmed-meshheading:17687824-Case-Control Studies,
pubmed-meshheading:17687824-Chest Pain,
pubmed-meshheading:17687824-Chi-Square Distribution,
pubmed-meshheading:17687824-Coronary Angiography,
pubmed-meshheading:17687824-Coronary Artery Disease,
pubmed-meshheading:17687824-Female,
pubmed-meshheading:17687824-Homocysteine,
pubmed-meshheading:17687824-Humans,
pubmed-meshheading:17687824-Logistic Models,
pubmed-meshheading:17687824-Male,
pubmed-meshheading:17687824-Middle Aged,
pubmed-meshheading:17687824-ROC Curve,
pubmed-meshheading:17687824-Risk Factors,
pubmed-meshheading:17687824-Sensitivity and Specificity,
pubmed-meshheading:17687824-Statistics, Nonparametric,
pubmed-meshheading:17687824-Turkey
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pubmed:articleTitle |
Diagnostic value of homocysteine, C-reactive protein and bilirubin for coronary artery disease.
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pubmed:affiliation |
Department of Biochemistry, Gaziantep University Medical School, Gaziantep, Turkey. necatyilmaz@hotmail.com
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pubmed:publicationType |
Journal Article,
Validation Studies
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