Linked Life Data

17686634

Source:http://linkedlifedata.com/resource/pubmed/id/17686634

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-9-17
pubmed:abstractText
We introduce a new unsupervised fMRI analysis method based on kernel canonical correlation analysis which differs from the class of supervised learning methods (e.g., the support vector machine) that are increasingly being employed in fMRI data analysis. Whereas SVM associates properties of the imaging data with simple specific categorical labels (e.g., -1, 1 indicating experimental conditions 1 and 2), KCCA replaces these simple labels with a label vector for each stimulus containing details of the features of that stimulus. We have compared KCCA and SVM analyses of an fMRI data set involving responses to emotionally salient stimuli. This involved first training the algorithm (SVM, KCCA) on a subset of fMRI data and the corresponding labels/label vectors (of pleasant and unpleasant), then testing the algorithms on data withheld from the original training phase. The classification accuracies of SVM and KCCA proved to be very similar. However, the most important result arising form this study is the KCCA is able to extract some regions that SVM also identifies as the most important in task discrimination and these are located manly in the visual cortex. The results of the KCCA were achieved blind to the categorical task labels. Instead, the stimulus category is effectively derived from the vector of image features.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1053-8119
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1250-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Unsupervised analysis of fMRI data using kernel canonical correlation.
pubmed:affiliation
The Centre for Computational Statistics and Machine Learning, Department of Computer Science, University College London, UK. D.Hardoon@cs.ucl.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't