Linked Life Data

17681597

Source:http://linkedlifedata.com/resource/pubmed/id/17681597

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
31
pubmed:dateCreated
2007-8-21
pubmed:abstractText
A limiting factor in regenerating large organs and healing large wounds completely is the inability to provide oxygen to the affected areas for vascularization and healing to occur. An oxygen rich compound of sodium percarbonate was incorporated into films of Poly(D,L-lactide-co-glycolide) (PLGA) and used for in situ production of oxygen. Oxygen release could be observed from the film over a period of 24 h. When the oxygen producing biomaterials were placed in contact with ischemic tissue in a mouse model, decreased tissue necrosis and cellular apoptosis was observed. This indicates that improved tissue viability could be maintained for several days using oxygen producing biomaterials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0142-9612
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4628-34
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Oxygen producing biomaterials for tissue regeneration.
pubmed:affiliation
Wake Forest Institute for Regenerative Medicine, Wake Forest University, Medical Center Boulevard, Winston-Salem, NC 27157, USA. bharriso@wfubmc.edu
pubmed:publicationType
Journal Article