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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-2-18
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pubmed:abstractText |
This report concerns the first cytogenetical study of a benign salivary gland oncocytoma. The cultured tumor was studied in five consecutive preparations. The first three were dominated by cells with a normal karyotype. In the two subsequent preparations a hyperdiploid stemline characterized by trisomy 7 had taken over. Trisomy 7 has previously been observed in a number of different, benign, premalignant and malignant conditions. We interpreted trisomy 7 in the salivary gland oncocytoma, as in these other conditions, to be a neoplasia-related, probably primary, gross chromosomal change and not an expression of aging or comparable events in normal cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1735-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1768045-Adenoma,
pubmed-meshheading:1768045-Aged,
pubmed-meshheading:1768045-Aged, 80 and over,
pubmed-meshheading:1768045-Chromosome Aberrations,
pubmed-meshheading:1768045-Chromosome Disorders,
pubmed-meshheading:1768045-Chromosomes, Human, Pair 7,
pubmed-meshheading:1768045-Humans,
pubmed-meshheading:1768045-Karyotyping,
pubmed-meshheading:1768045-Male,
pubmed-meshheading:1768045-Parotid Neoplasms,
pubmed-meshheading:1768045-Trisomy
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pubmed:articleTitle |
Benign parotid oncocytoma with the chromosomal abnormality trisomy 7.
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pubmed:affiliation |
Department of Pathology and Cytogenetics, Central Hospital, Skövde, Sweden.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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