Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
30
pubmed:dateCreated
2007-7-26
pubmed:abstractText
Perceptual decisions are likely to be based on signals that are provided by populations of neurons in early sensory cortical areas. How these neural responses are combined across neurons and over time to mediate behavior is unknown. To study the link between neural responses and perceptual decisions, we recorded the activity of single units (SU) and multiple units (MU) in the primary visual cortex (V1) of monkeys while they performed a reaction-time visual detection task. We then determined how well the target could be detected from these neural signals. We found that, on average, the detection sensitivities supported by SU and MU in V1 are comparable with the detection sensitivity of the monkey even when considering neural responses during brief temporal intervals (median duration, 137 ms) that ended shortly before the monkey's reaction time. However, we observed systematic differences between the overall shape of the neurometric functions and the monkey's psychometric functions. We also examined the quantitative relationship between SU and MU activity and found that MU responses are consistent with the sum of the responses of multiple SU, most of which have low stimulus selectivity. Finally, we found weak but significant trial-to-trial covariations between V1 activity and behavioral choices, demonstrating for the first time that choice probability can be observed at the earliest stages of cortical sensory processing. Together, these results suggest that the activity of a large population of V1 neurons is combined suboptimally by subsequent processing stages to mediate behavioral performance in visual detection tasks.
pubmed:grant
pubmed:commentsCorrections
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pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
25
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8122-37
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Linking neuronal and behavioral performance in a reaction-time visual detection task.
pubmed:affiliation
Department of Psychology and Center for Perceptual Systems, University of Texas at Austin, Austin, Texas 78712, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural