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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-7-19
pubmed:abstractText
Several studies have indicated association between hematologic markers and increased risks of cerebrovascular disease, but few reports referred to their roles together. We studied plasma levels of 16 hematologic markers in 50 cases diagnosed as acute cerebral infarction (ACI) and 54 hospital control subjects. Plasma levels of thrombomodulin, fibrinogen, and activity of tissue factor (aTF) were significantly higher in cases than in control subjects (P < .001, P < .01, and P < .05, respectively). Multivariate logistic regression analysis showed that hypertension and high plasma levels of thrombomodulin, fibrinogen, and aTF were significantly associated with presence of ACI (odds ratio [OR], 143.74, P < .001; OR, 2.05, P < .05; OR, 2.09, P < .05; OR, 1.02, P < .05, respectively). Our findings indicate that hypertension and elevation of plasma thrombomodulin, fibrinogen, and aTF are independent risk factors for ACI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-92
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Plasma thrombomodulin, fibrinogen, and activity of tissue factor as risk factors for acute cerebral infarction.
pubmed:affiliation
Institute of Hematology, Affiliated Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't