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rdf:type |
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lifeskim:mentions |
umls-concept:C0001721,
umls-concept:C0005400,
umls-concept:C0021368,
umls-concept:C0026809,
umls-concept:C0065067,
umls-concept:C0205191,
umls-concept:C0205292,
umls-concept:C0205373,
umls-concept:C0221908,
umls-concept:C0699748,
umls-concept:C1314939,
umls-concept:C1883709
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pubmed:issue |
5
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pubmed:dateCreated |
2007-7-6
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pubmed:abstractText |
Chronic colitis-harboring TCRalpha(- / - ) x AIM(- / - ) mice showed PBC-like bile duct damage in the liver. Bacterial infection is one of the candidates for the pathogenesis of PBC. We demonstrated that the bacterial cell wall component lipotheicoic acid (LTA) was detected at sites of inflammation around damaged bile ducts in PBC patients. The aim of this study was to investigate the pathophysiology of the liver and other organs in TCRalpha(- / - ) x AIM(- / - ) mice.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11230731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11294859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11388391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11391535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11401975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-11580136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-12598318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-1500175,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-15479645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-15601766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-16119989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-16326135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-16553825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-16698669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-2090151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-2187198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-3289326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-7479784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-7536796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-9756487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17612899-9892623
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0891-6934
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
372-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17612899-Animals,
pubmed-meshheading:17612899-Bile Ducts, Intrahepatic,
pubmed-meshheading:17612899-Chronic Disease,
pubmed-meshheading:17612899-Colitis,
pubmed-meshheading:17612899-Epithelium,
pubmed-meshheading:17612899-Female,
pubmed-meshheading:17612899-Gram-Positive Bacteria,
pubmed-meshheading:17612899-Inflammation,
pubmed-meshheading:17612899-Intestine, Small,
pubmed-meshheading:17612899-Kidney,
pubmed-meshheading:17612899-Lipopolysaccharides,
pubmed-meshheading:17612899-Liver,
pubmed-meshheading:17612899-Liver Cirrhosis, Biliary,
pubmed-meshheading:17612899-Mice,
pubmed-meshheading:17612899-Pancreas,
pubmed-meshheading:17612899-Spleen,
pubmed-meshheading:17612899-Teichoic Acids
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pubmed:year |
2007
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pubmed:articleTitle |
Lipoteichoic acid may affect the pathogenesis of PBC-like bile duct damage and might be involved in systemic multifocal epithelial inflammations in chronic colitis-harboring TCRalpha-/-xAIM-/- mice.
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pubmed:affiliation |
Department of Medicine and Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan. haruta@ige.twmu.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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